Author's response to reviews Title:Mortality attributable to Plasmodium vivax malaria: a clinical audit from Papua Indonesia Authors:
نویسندگان
چکیده
Nicholas M Douglas ([email protected]) Gysje J Pontororing ([email protected]) Daniel A Lampah ([email protected]) Tsin W Yeo ([email protected]) Enny Kenangalem ([email protected]) Jeanne Rini Poespoprodjo ([email protected]) Anna P Ralph ([email protected]) Michael J Bangs ([email protected]) Paulus Sugiarto ([email protected]) Nicholas M Anstey ([email protected]) Ric N Price ([email protected])
منابع مشابه
Mortality attributable to Plasmodium vivax malaria: a clinical audit from Papua, Indonesia
BACKGROUND Plasmodium vivax causes almost half of all malaria cases in Asia and is recognised as a significant cause of morbidity. In recent years it has been associated with severe and fatal disease. The extent to which P. vivax contributes to death is not known. METHODS To define the epidemiology of mortality attributable to vivax malaria in southern Papua, Indonesia, a retrospective clinic...
متن کاملMefloquine is highly efficacious against chloroquine-resistant Plasmodium vivax malaria and Plasmodium falciparum malaria in Papua, Indonesia.
BACKGROUND During the period of 1996-1999, we prospectively monitored 243 Javanese adults and children after arriving in Papua, Indonesia, and microscopically documented each new case of malaria by active surveillance. METHODS In a randomized, open-label, comparative malaria treatment trial, 72 adults and 50 children received chloroquine for each incident case of malaria, and 74 adults and 47...
متن کاملRandomized, placebo-controlled trial of atovaquone/proguanil for the prevention of Plasmodium falciparum or Plasmodium vivax malaria among migrants to Papua, Indonesia.
The increasing prevalence of resistance to antimalarial drugs reduces options for malaria prophylaxis. Atovaquone/proguanil (Malarone; GlaxoSmithKline) has been >95% effective in preventing Plasmodium falciparum malaria in lifelong residents of areas of holoendemicity, but data from persons without clinical immunity or who are at risk for Plasmodium vivax malaria have not been described. We con...
متن کاملMultidrug-Resistant Plasmodium vivax Associated with Severe and Fatal Malaria: A Prospective Study in Papua, Indonesia
BACKGROUND Multidrug-resistant Plasmodium vivax (Pv) is widespread in eastern Indonesia, and emerging elsewhere in Asia-Pacific and South America, but is generally regarded as a benign disease. The aim of the study was to review the spectrum of disease associated with malaria due to Pv and P. falciparum (Pf) in patients presenting to a hospital in Timika, southern Papua, Indonesia. METHODS AN...
متن کاملSevere Malarial Thrombocytopenia: A Risk Factor for Mortality in Papua, Indonesia
BACKGROUND The significance of thrombocytopenia to the morbidity and mortality of malaria is poorly defined. We compared the platelet counts and clinical correlates of patients with and those without malaria in southern Papua, Indonesia. METHODS Data were collated on patients presenting to a referral hospital between April 2004 and December 2012. RESULTS Platelet measurements were available...
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